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Iswarya Fertility Centre & Women's Hospital
Iswarya
Fertility Centre
General

Recurrent Pregnancy Loss

Recurrent pregnancy loss (3 or more miscarriages) has identifiable causes in most cases, and a tailored treatment plan can achieve a successful pregnancy.

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Overview

What is Recurrent Pregnancy Loss?

Recurrent Pregnancy Loss (RPL) is defined as two or more consecutive pregnancy losses. It affects 1–2% of couples and causes significant emotional distress. Despite its frequency, thorough investigation uncovers a causative or contributory factor in approximately 50% of cases — and with appropriate treatment, most couples eventually achieve a live birth.

Comprehensive RPL Care at Iswarya Fertility

Our RPL clinic evaluates chromosomal, anatomical, endocrine, thrombophilic, and immunological factors. Treatment protocols may include progesterone supplementation, low-molecular-weight heparin, immunotherapy, PGT-A embryo selection, or uterine surgery depending on the identified cause.

Symptoms

Two or more consecutive pregnancy losses
Losses typically occurring in the first trimester
History of normal fertility but inability to sustain pregnancy
Emotional distress, anxiety around subsequent pregnancies
History of thrombotic events

Causes

1
Chromosomal abnormalities in embryo (most common — ~50% of losses)
2
Antiphospholipid syndrome (APS) — thrombophilia
3
Uterine abnormalities: septum, fibroids, polyps, adhesions
4
Thyroid disorders and uncontrolled diabetes
5
Inherited thrombophilias (Factor V Leiden, MTHFR)

How It's Diagnosed

Antiphospholipid antibody panel (lupus anticoagulant, anticardiolipin)
Parental karyotyping to detect chromosomal translocations
Hysteroscopy / 3D ultrasound to assess uterine anatomy
Thrombophilia screen and thyroid function tests

Take the First Step

Get a personalised treatment plan for Recurrent Pregnancy Loss from our fertility specialists

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Recurrent Pregnancy Loss — Causes, Symptoms & IVF Treatment | Iswarya Fertility | Iswarya Fertility