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Iswarya Fertility Centre & Women's Hospital
Iswarya
Fertility Centre
Male Infertility

Male Hormonal Imbalance

Hormonal imbalances in men — including low testosterone or high oestrogen — reduce sperm production and can often be corrected medically.

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Overview

Male Hormonal Imbalance and Fertility

Sperm production is tightly regulated by a hormonal cascade: GnRH from the hypothalamus drives LH and FSH from the pituitary, which in turn stimulate testosterone production and spermatogenesis in the testes. Disruption at any level — low testosterone, elevated oestradiol, elevated prolactin, or hypogonadotrophic hypogonadism — reduces sperm production and quality.

Medical Therapy at Iswarya Fertility

Our andrologists tailor hormonal therapy using clomiphene citrate, hMG, FSH injections, or dopamine agonists to restore the hormonal axis and improve sperm parameters, often making IVF unnecessary.

Symptoms

Low libido and reduced sexual drive
Erectile dysfunction
Fatigue and reduced muscle mass
Poor semen parameters on analysis
Gynaecomastia (breast tissue development)

Causes

1
Hypogonadotrophic hypogonadism (pituitary/hypothalamic failure)
2
Hyperprolactinaemia suppressing testosterone
3
Anabolic steroid or testosterone supplement use
4
Obesity increasing conversion of testosterone to oestrogen
5
Kallmann syndrome (genetic GnRH deficiency)

How It's Diagnosed

Serum FSH, LH, total testosterone, oestradiol
Serum prolactin and thyroid function
MRI pituitary (if secondary hypogonadism suspected)

Take the First Step

Get a personalised treatment plan for Male Hormonal Imbalance from our fertility specialists

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Male Hormonal Imbalance — Causes, Symptoms & IVF Treatment | Iswarya Fertility | Iswarya Fertility