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Iswarya Fertility Centre & Women's Hospital
Iswarya
Fertility Centre
99627-00000
General

Embryo Arrest and Poor Embryo Quality

Embryos fail to develop beyond early cleavage or show fragmentation and arrest. Often reflects oocyte mitochondrial dysfunction or chromosomal abnormality.

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Overview

Overview

Embryos fail to develop beyond early cleavage or show fragmentation and arrest. Often reflects oocyte mitochondrial dysfunction or chromosomal abnormality.

Symptoms

Embryos stop dividing between day 2–5
High fragmentation rates
No blastocysts formed
Repeated across multiple cycles

Causes

1
Oocyte quality (mitochondrial dysfunction, aneuploidy)
2
Maternal age
3
Sperm DNA damage
4
Genetic mutations (TUBB8, NLRP5)

How It's Diagnosed

PGT-A
Sperm DNA fragmentation test
Time-lapse embryo morphokinetics
Female karyotype

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Embryo Arrest and Poor Embryo Quality — Causes, Symptoms & Treatment | Iswarya Fertility | Iswarya Fertility