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Iswarya Fertility Centre & Women's Hospital
Iswarya
Fertility Centre
Female Infertility

Cushing Syndrome

Prolonged exposure to high cortisol levels disrupts the HPG axis, suppressing ovulation and causing metabolic and reproductive dysfunction.

Overview

Overview

Prolonged exposure to high cortisol levels disrupts the HPG axis, suppressing ovulation and causing metabolic and reproductive dysfunction.

Symptoms

Central weight gain
Moon face
Purple striae
Irregular or absent periods
Infertility
Hypertension

Causes

1
Pituitary adenoma
2
Adrenal adenoma
3
Ectopic ACTH secretion
4
Exogenous steroid use

How It's Diagnosed

24-hour urinary cortisol
Overnight dexamethasone suppression test
Morning cortisol
MRI pituitary/adrenal

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